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【学术活动预告】Global Metabolomics: from Innovation to Integration

报告题目: Global Metabolomics: from Innovation to Integration

报告专家: 还涛 博士 加拿大不列颠哥伦比亚大学助理教授

时间:2018年6月20日(周三)上午10:00.

地点:化行楼226

报告摘要:

Global metabolomics is an emerging field in postgenomic biology that correlates the comprehensive analysis of small molecules in biological systems with phenotypes and biological processes. Over the past 15 years, there have been many innovative developments in analytical strategies and informatics, making it possible to integrate metabolomic analysis with orthogonal omics (i.e. genomics, transcriptomics, proteomics) to garner systems-level information on the biological function of metabolites. This seminar will focus on current progresses in analytical technologies and bioinformatics that address the challenges in global metabolomics, including metabolomic data processing and metabolite identification. Advancing from innovation to integration, a recently developed metabolomics-guided systems biology platform will be introduced, which can provide a mechanistic understanding of metabolomic data through multi-omic integration aimed at identifying dysregulated metabolic pathways. To illustrate the importance of integrative metabolomic analysis in deciphering biological causality, a specific case study in cancer metabolism, on identifying aberrant metabolic pathways involved in colon cancer progression, will be discussed.

专家概况:

还涛博士现为加拿大不列颠哥伦比亚大学助理教授。2010年本科毕业于浙江大学,2015年在阿尔伯塔大学获得博士学位。2015年-2018年间在斯克里普斯研究所做博士后研究。还涛博士主要研究方向为基于质谱的分析技术研发和生物信息学App开发,利用代谢组学技术研究健康和疾病相关的生命医知识题。目前已在综合或专业领域内权威期刊(Nature Methods, Nature Protocols, Cell reports, Cell Chemical Biology, Analytical Chemistry)等发表论文近 30 篇。

发布时间:2018/06/14
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